| Day 1 (Thursday, September 15, 2016) |
Session 1
Chair: Silvio Tosatto |
| 08:00 - 09:00 | Registration |
| 09:00 - 09:10 | Nevena Veljkovic, Serbia
Welcome |
| 09:10 - 09:30 | Silvio Tosatto, Italy
Introduction to NGP-net |
| 09:30 - 10:00 | Burkhard Rost, Germany
Implications of dark proteome for personalized health |
| 10:00 - 10:30 | Rohit Pappu, USA
Conformations and molecular functions encoded by sequence patterns of non-globular proteins |
| 10:30 - 10:50 | Andrey Kajava, France
A Census of Tandem Repeats in Proteomes |
| 10:50 - 11:20 | Coffee break |
Session 2
Chair: Sonia Longhi |
| 11:20 - 11:50 | Stefano Gianni, Italy
Understanding the mechanisms of folding and binding of intrinsically disordered proteins |
| 11:50 - 12:20 | Edward Lemke, Germany
Decoding Molecular Plasticity in the Dark Proteome |
| 12:20 - 12:40 | Arne Elofsson, Sweden
High GC Content Causes Young Proteins to be Intrinsically Disordered |
| 12:40 - 13:00 | Flash presentations |
| 13:00 - 15:00 | Lunch & Poster session (Odd numbered posters) |
Session 3
Chair: Rohit Pappu |
| 15:00 - 15:30 | Ehud Gazit, Israel
From Biological Self-Assembly to Novel Peptide Nanostructures of Unique Mechanical, Optical, Piezoelectric and Semiconductive Properties |
| 15:30 - 16:00 | Johnny Habchi, UK
Systematic development of small molecules and characterization of their effect on ΑΒ42 aggregation at a single microscopic step level |
| 16:00 - 16:20 | Aitziber L. Cortajarena, Spain
Designed proteins scaffolds to stabilize nanoclusters: sensing and imaging appliactions |
| 16:20 - 16:40 | Pietro Sormanni, UK
Rational design of binding proteins targeting specific epitopes within intrinsically disordered proteins |
| 16:40 - 17:10 | Coffee break |
Session 4
Chair: Arne Elofsson |
| 17:10 - 17:40 | Norman Davey, Ireland
Discovery and Characterisation of Novel Functional Modules in Intrinsically Disordered Regions |
| 17:40 - 18:00 | Edoardo Salladini, France
Preliminary characterization of the Henipavirus V protein and its interaction with the cellular protein DDB1 |
| 18:30 | Belgrade tour and dinner at the restaurant Gabiano (http://gabbiano.rs/) |
| Day 2 (Friday, September 16, 2016) |
Session 5
Chair: Stefano Gianni |
| 9:00 - 9:30 | Alasdair Steven, USA
Order-Disorder Transitions of Coiled-coil Barrels During Virus Assembly |
| 9:30 - 10:00 | Fabrizio Chiti, Italy
The mechanism of aggregation of non-globular proteins |
| 10:00 - 10:20 | Salvador Ventura, Spain
Repositioning Tolcapone as a potent inhibitor of transthyretin amyloidogenesis and its associated cellular toxicity |
| 10:20 - 10:40 | Ramon Crehuet, Spain
Modelling Intrinsically Disordered Proteins. Challenges when comparing to experiments |
| 10:40 - 11:10 | Coffee break |
Session 6
Chair: Andrey Kajava |
| 11:10 - 11:40 | Diego Ferreiro, Argentina
Inferring folding energy landscapes from repeat-protein sequences |
| 11:40 - 12:10 | Fabio Parmeggiani, UK
Novel repeat protein families: design, assembly and polymerization |
| 12:10 - 12:30 | Lisanna Paladin, Italy
Tandem Repeat proteins at a glance: functions, diseases and role in protein-protein interaction network |
| 12:30 - 12:55 | Flash presentations |
| 13:00 - 15:00 | Lunch & Poster session (Even numbered posters) |
Session 7
Chair: Isabelle Landrieu |
| 15:00 - 15:30 | Philippe Minard, France
AlphaRep: a library of artificial repeat proteins as an efficient source of specific binding proteins |
| 15:30 - 15:50 | Elena Papaleo, Denmark
To unravel at the atom-level intrinsically disordered proteins and the effects induced by cancer alterations integrating enhanced sampling simulations and biophysical techniques |
| 15:50 - 16:10 | Turkan Haliloglu, Turkey
Collective Dynamics and Modulation of Function |
| 16:10 - 16:30 | San Hadzi, Slovenia
Intrinsic disorder is at hart of the ratio-dependent autoregulation in two-gene bacterial operon |
| 16:30 - 17:00 | Coffee break |
Session 8
Chair: Salvador Ventura |
| 17:00 - 17:30 | Simon Alberti, Germany
Three complementary mechanisms of quality control ensure RNP granule functionality and dynamics |
| 17:30 - 17:50 | Bente Vestergaard, Denmark
Structural Studies of Amyloid-like Protein Fibrillation |
| 17:50 - 18:10 | Oxana Galzitskaya, Russia
The mechanism underlying amyloid polymorphism is opened for Alzheimer's disease ΑΒ peptide |
| 18:10 - 18:30 | Mariana Amoroso das Neves Romão, Portugal
S100 proteins as novel modifiers of proteostasis in health and disease |
| 18:30 - 18:50 | Lucia Chemes, Argentina
Linear motif combination and conservation of flexibility determines the displacement ability of an intrinsically disordered viral oncoprotein |
| 20:00 | Dinner at the hotel |
| Day 3 (Saturday, September 17, 2016) |
Session 9
Chair: Alasdair Steven |
| 9:00 - 9:30 | Rob Finn, UK
Recognising intrinsically disordered regions in protein family databases |
| 9:30 - 10:00 | Andrei Lupas, Germany
Coiled coils - between structure and unstructured |
| 10:00 - 10:20 | Pau Bernado, France
Disentangling polydispersity for the PCNA-p15 interaction: A disordered, transient and multivalent macromolecular assembly |
| 10:20 - 10:40 | Georgios Skretas, Greece
Molecular evolution of short cyclic peptides that rescue the misfolding, aggregation, and the associated pathogenic effects of proteins linked to protein misfolding diseases |
| 10:40 - 11:10 | Coffee break |
Session 10
Chair: Zsuzsanna Dosztanyi |
| 11:10 - 11:40 | Laura Itzhaki, UK
Engineering folding and function of tandem-repeat proteins |
| 11:40 - 12:00 | Isabelle Landrieu, France
Modulation of neuronal tau protein interaction with protein partners |
| 12:00 - 12:20 | Diana Fedunova, Slovakia
Inhibiting activity of fullerenol C60(OH)16 on ΑΒ1-40 amyloid aggregation - in vitro and in silico study |
| 12:20 - 12:55 | Flash presentations |
| 12:55 - 13:00 | Nevena Veljkovic, Serbia
Closing remarks |
| 13:00 - 14:30 | Lunch |
| 14:30 - 16:30 | WG Meetings |
| 16:30 - 17:00 | Coffee break |
| 17:00 - 17:30 | WG leaders
WG meeting summaries |
| 17:30 - 18:30 | Planning for projects |
| 20:00 | Dinner at Mali vrabac (http://www.malivrabac.rs/) |
