Name: Veljko Veljković
Date of Birth: January 17, 1947
Place of Birth: Belgrade, Yugoslavia
Address: Institute of Nuclear Science
VINCA, Center for Multidisciplinary Research,
P.O. BOX 522, 11001 Belgrade,
Yugoslavia
E-mail address: druid@beotel.yu
Phone: (+381) 11 2440 871
Fax: (+381) 11 45 36 86
PhD, 1973, Theoretical Physics, University of Belgrade.
MS, 1971, Chemical Engineering, University of Belgrade.
BSc, 1969, Metallurgy, University of Belgrade.
Laboratory for Theoretical Physics, Institute of Nuclear Science Vinca
Belgrade, Yugoslavia (1969 – 1985)
Research area: Solid state physics, Material science, Biophysics
Center for Multidisciplinary Research, Institute of Nuclear Science Vinca, Belgrade, Yugoslavia (1986 – present)
Research area: Bioinformatics, Protein engineering, AIDS research, Material science
1969-1975 Solid state physics: Development of the general model pseudopotential and its application in research of electronic properties, phonon spectra and superconductivity of metals and intermetallic compounds.
1976-1980 Biophysics: Chemical carcinogenesis, toxicology and molecular pharmacology
1981-1987 Bioinformatics: Development of the informational spectrum method and its application in structure/function analysis of nucleotide and protein sequences
1988-present AIDS research: Interactions between HIV envelope protein and immune system and role of the molecular mimicry in pathogenesis of AIDS.
Bioinformatics: Structure/function analysis of protein and nucleotide sequences.
Nuclear waste management and remediation: Investigation of stability of solid matrix – impurity systems
Monographs
Veljković V. Theoretical approach to preselection of cancerogens and chemical carcinogenesis. Gordon & Breach, New York, 1980.
Veljković V., Metlaš R. AIDS Vaccine: between hopes and possibility. Institut za nuklearne nauke VINČA, Vinča (1993).
Veljković V., Jevtović Dj. Fizičko vežbanje u preventivi i terapiji HIV infekcije i raka. Monada, Beograd (2001).
Articles published in international journals
Solid State Physics
Pseudopotential theory
1. Veljković V, Slavić I. Simple general-model pseudopotential. Phys. Rev. Let., 29, 105 (1972).
2. Veljković V. The dependence of the Fermi energy on the atomic number. Phys. Lett., 45A, 41 (1973).
3. Veljković V., Lalović D. General model pseudopotential for positive ions. Phys. Lett., 45A, 59 (1973).
Superconductivity
4. Veljković V., Lalović D., Superconductivity and the periodic system. Phys. Rev., 11, 4242 (1975).
5. Veljković V., Janjić J., Tošić B. Ion-ion interaction and superconductivity of metals and intermetallic compounds. J. Mater. Sci., 13, 1138 (1978).
6. Veljković V., Lalović D., A stoichiometry criterion for high Tc superconductors. Phys. Lett. A, 142 528 (1989).
Material science
7. Veljković V., Tošić B., Janjić J., Chemical bond in intermetallic compounds and its influence on electrical properties. Scr. Metall., 9, 459 (1975).
8. Blažon M., Stanojević B., Veljković V., Effect of alloying elements on the formation of boride layer on steel. Scr. Metall., 9, 1153 (1975).
9. Vukajlović F., Zeković S., Veljković V., Resistivity calculations for liquid metals. Physica, 92B, 66 (1977).
10. Davidović M., Vukajlović F., Zeković S., Veljković V. The temperature dependence of the resistivity of liquid lead. Phil. Mag., 36, 1257 (1977).
11. Zeković S., Vukajlović F., Veljković V. Phonon spectra of alkali metals, Physica, 114B, 316 (1982).
Chemical carcinogenesis and molecular pharmacology
12. Veljković V., Lalović D., Theoretical prediction of mutagenicity and carcinogenicity of chemical substances. Cancer Biochem. Biophys., 1, 295 (1976).
13. Veljković V., Lalović D., Simple theoretical criterion of chemical carcinogenesis. Experientia, 33, 1228 (1977).
14. Veljković V., Lalović D., Correlation between the carcinogenicity of organic substances and their spectral characteristics. Experientia, 34, 1342 (1977).
15. Veljković V., Ajdačić V., Cytostatic activity of organic compounds and their average quasi-valence number. Experientia, 34, 639 (1977).
16. Ajdačić V., Veljković V. Antibiotic activity of organic compounds and their average quasi-valence number. Experientia, 34, 633 (1977).
17. Veljković V., Ćosić I., Dimitrijević B., Lalović D., Is it possible to analyze DNA and protein sequence by the method of digital signal processing?. IEEE Trans., BME-32, 337 (1985).
18. Veljković V., Ćosić I., A novel method of protein analysis for prediction of biological function. Cancer Biochem. Biophys., 9, 139 (1987).
19. Veljković V., Lalović D. The global average DNA base composition of coding regions may be determined by the electron-ion interaction potential. Biosystems, 23, 311 (1990).
20. Veljković V., Metlaš R., Identification of nanopeptide from HTLV3, LAV and ARV-2 envelope gp120 determining binding to T4 cell surface protein. Cancer Biochem. Biophys., 10, 191 (1988).
21. Veljković V., Metlaš R., Sequence similarity between HIV-1 envelope protein gp120 and human proteins: a new hypothesis on protective antibody production. Immunol. Lett., 26, 193 (1990).
22. Metlaš R., Veljković V., Paladini R., Pongor S., Protein and DNA sequence similarity between the V3 loop of HIV-1 envelope protein gp120 and immunoglobulin variable region. Biochem. Biophys. Res. Commun., 179, 1056 (1991).
23. Veljković V., Metlaš R., Identification of immunoglobulin recombination elements in in HIV-1 envelope gene. Immunol.Lett., 31, 11 (1991).
24. Veljković V., Metlaš R., HIV and idiotypic T-cel regulation: another view., Immunol. Today, 15, 39 (1992).
25. Veljković V., Metlaš R., Raspopović J., Pongor S., Spectral and sequence similarity between VIP and the second conserved region of HIV envelope glycoprotein gp120: possible consequences on prevention and therapy of AIDS., Biochem. Biophys. Res. Commun., 189, 705(1992).
26. Veljković V., Metlaš R., Potentially negative effects of AIDS vaccines Based on recombinant viruses carrying HIV-1 derived envelope gene: a warning on AIDS vaccine development., Vaccine, 11, 291 (1993).
27. Veljković V., Metlaš R., Vojvodić D., Čavor Lj., Pejinović N., Dujić A., Zakhariev S., Guarnaccia C., Pongor S., Natural autoantibodies cross-react with a peptide derived from the second conserved region of HIV-1 envelope glycoprotein gp120., Biochem. Biophys. Res. Commun. 196, 1019 (1993).
28. Metlaš R. Veljković V., Does HIV-1 gp120 manipulate human immune network. Vaccine 13, 355 (1995).
29. Metlaš R., Skerl V., Colombatti A., Pongor S., Veljković V. Reactivity of AIDS patients sera with peptide derived from HIV-1 NY5 gp120 V3 loop and consensus sequence of collagens. AIDS Res. & Human Retrovir. 10, 1421 (1994).
30. Metlaš R., Skerl V., Veljković V., Colombatti A., Pongor S., Immunoglobulin-like domain of HIV-1 envelope glycoprotein gp120 encodes putative internal image of some common human proteins. Viral Immunol. 7, 215 (1994).
31. Metlaš R., Skerl V., Veljković V., Pongor S., Further evidence for the relationship between HIV-1 gp120 V3 loop and T cell receptor delta-chain structures. Immunol. Lett. 47, 25 (1995).
32. Veljković V., Johnson E., Metlaš R. Analogy of HIV-1 to oncogenic viruses: possible implications for the pathogenesis of AIDS. Cancer J. 8, 308 (1995).
33. Veljković V., Johnson E., Metlaš R. Molecular basis of the inefficacy and possible harmful effects of AIDS vaccine candidates based on HIV-1 envelope glycoprotein gp120. Vaccine 15, 437 (1997).
34. Prljic J., Veljković N., Doliana R., Colombatti A., Johnson E., Metlaš R., Veljković V. Identification of an complete and active recombinational hot spot within the HIV-1 gp120 gene: possible implications for the AIDS vaccine development. Vaccine, 17, 1462 (1999).
35. Metlaš R., Trajkovic D., Srdic T., Veljković V., Colombatti A. Human immunodeficency virus V3 peptide-reactive antibodies are present in normal HIV-negative sera. AIDS Res. Hum. Retrovir., 15, 671 (1999).
36. Metlaš R., Trajković D. Srdic T., Veljković V. Colombatti A. Anti-V3 and anti-IgG antibodies of healthy individuals share complementarity structures J. Acquir. Immune. Defic. Synd., 21, 266 (1999).
37. Veljković V., Metlaš R., Kohler H., Urnovitz H.B., Prljić J., Veljković N., Johnson E., Muller S. AIDS epidemic at the beginning of the third millennium: time for a new AIDS vaccine strategy. Vaccine, 19, 1855 (2001).
38. Veljković V., Metlaš R., Jevtović Dj., Stringer W. The role of passive immunization in hiv-positive patients : a case report. Chest, 120, 662 (2001).
39. Kohler H., Muller S., Veljković V., No hope for an AIDS vaccine soon. AIDScience, 2, 5 (2002).
40. Veljković V., Muller S., Kohler H. Does VaxGen hide the breakthrough Infections. Lancet, 361, 1743 (2003).
41. Veljković V., Branch D.R., Metlaš R., Prljić J., Vlahovicek K., Pongor S., Veljković V. Design of peptide mimetics of HIV-1 gp120 for prevention And therapy of HIV disease. J. Pep. Res., 62, 1 (2003).
42. Veljković V., Muller S., Kohler H. AIDSVAX results: an important open question. Vaccine, 21, 3528 (2003).
Articles published in Yugoslav journals
1. Saboljev S, Zunić Z., Veljković V. Radijaciona rezistencija mikroorganizama poreklom iz plovnih objekata ratne mornarice. Pomorska medicina, 30, 205 (1979).
2. Veljković V., Vojvodić V. Teorijske mogu~nosti za izra~unavanje stetnih uticaja pojedinih hemikalija na `ive organizme. Arhiv Hig. Rada i Toksikol., 32, 311 (1981).
3. Veljković V., Metlaš R. New insight into HIV gp120/ CD4 interactions. Iugoslav. Phisiol. Pharmacol. Acta, 26, 259 (1990).
4. Metlaš R., Veljković V. Are HIV infected cells prone to illegitimate gene recombination and intrathymic deletion. Phisiol. Pharmacol. Acta, 29, 259 (1993).
5. Metlaš R. Vojvodić D., Pejnović N., Skerl V., Pavlović M., Dujić D., Veljković V. Affinity-purified antibodies from AIDS patients serum react with synthetic peptides derived from HIV-1 (NY5) gp120 V3 loop and collagens. Phisiol. Pharmacol. Acta, 30, 245 (1990).
Articles published in proceedings of international conferences
1. Vojvodić V., Veljković V., Lalović D., Cosić I. Simple theoretical test-method for detection of supertoxic organophosphorous compounds as potential CWA. Proc. 1st Int. Symp. on Protection Against Chemical Warfare Agents, Stocholm, June 1983, pp. 271-275.
2. Veljković V., Čosić I., Lalović D. New method for amalysis of genetic information. Proc. 3th Mediterranean Conf on Biomedical Engineering, Portorož, Sept. 1983, pp. 47-49.
3. Vojvodić V., Veljković V., Lalović D., Čosić I. Correlation between some physical parameters and toxicity and alkaline hydrolysis rate constants of organophosphorous compounds. Proc. 1st World Congress on New Compounds in Biological and Chemical Warfare, Genth, May 1984, pp. 276-282.
4. Cosić I., Marinković M., Veljković V. Transfer functions of acupuncture meridians. Digital Signal Processing.-84, Florence, Oct. 1984, pp. 673-675.
5. Vojvodić V., Skerl V., Veljković V. Theoretical prediction of the functional “hot spots” on the presynaptic protein toxins. Proc. 2nd Int. Symp. on Protection Against Chemical Warfare Agents, Stocholm, June 1986, pp. 303-309.
6. Vojvodić V., Skerl V., Veljković V. Possibilities in recognition of neurotransmiters and receptors applying informational spectrum method. Proc. 2nd Int. Symp. on Protection Against Chemical Warfare Agents, Stocholm, June 1986, pp. 347-358.
7. Raicević S., Plecaš I., Lalović D., Veljković V. Optimization of immobilization of strontium and uranium by the solid matrix, MRC Symp. Proc., 556, pp. 135-140 (1999).
International patents
Veljković V., Prljić J., Veljković N., Metlaš R.
NUCLEOTIDE SEQUENCE FOR DETECTION AND CHARACTERIZATION OF THE HIV-1 FIELD ISOLATES PARTICIPATING IN THE RECOMBINATION PROCESSES DIRECTED BY THE CHI SEQUENCE. EP01043407A3, 10/18/2000.
Veljković V., Metlaš R., Marković D.
POLYPEPTIDES MIMICKING THE ACTIVITY OF HUMAN ERYTHROPOIETIN. EP00928292A1, WO09749729A1, CA02258871AA, AU03435397A1, 07/14/1999.
Veljković V., Metlaš R., Marković D.
POLYPEPTIDER SOM ETTERAPER AKTIVITETEN TIL HUMANT ERYTROPOIETIN. NO00985993A, 02/24/1999.
Veljković V., Metlaš R.
POLYPEPTIDES INVOLVED IN THE INTERACTION OF HIV GP120 WITH THE FUSIN, AND THE CC-CKR-5 CO-RECEPTORS THEREOF. GB02319252A, 05/20/1998
Veljković V., Metlaš R.
PEPTIDES WHICH REACT WITH ANTIBOBY REPRESENTING THE PROGNOSTIC MARKER FOR HIV DISEASE PROGRESSION. EP00808846A3, GR98300031T1,
CA02205077AA, JP10237100A2, 08/26/1998
Veljković V., Metlaš R.
PEPTIDE, DIE MIT ANTIKOERPERN REAGIEREN, DIE DEN FORTSCHRITT DER HIV-ERKRANKUNG MARKIEREN. EP00808846TD, 06/25/1998.
Veljković V., Metlaš R.
PEPTIDOS QUE REACCIONAN CON ANTICUERPOS QUE REPRESENTAN EL MARCADOR DE PRONOSTICO DE LA PROGRESION DE LA ENFERMEDAD DEL SIDA. ES02113333T1,
05/01/1998
Veljković V., Prljić J., Veljković N., Metlaš R.
SEQUENZA NUCLEOTIDICA PER LA RIVELAZIONE E CARATTERIZZAZIONE DI ISOLATI OSPEDALIERI DI HIV-1 CHE PARTECIPANO NEI PROCESSI DI RECOMBINATIONI.
ITMI980776A0, 04/10/1998
Yugoslav patents
Cizelj V., Škokljev A., Čenćan D., Ajdačić V., Stamenović B, Desimirović V.,
Veljković V. Two-channel bioelectric apparatus for therapeutic purposes.
YU134482A (1985).
Veljković V., Ćosić I., Davidović D. Aerials made of carbon material. YU035285A (1988).