Ime i prezime: Dragan Alavantić

Datum rodjenja: 11.04.1954.

Datum diplomiranja: Februar 1977, Biološki fakultet, BU

Datum odbrane doktorata: Mart 1986, Biološki fakultet, BU

Naučno zvanje: Naučni savetnik

Podaci za kontakt: INN "Vinča"

Laboratorija za radiobiologiju i molekularnu genetiku – 080

p.fah 522, 11001 Beograd, Srbija

tel/fax: +381 (0)11 444 74 85

E-mail: adragan@vin.bg.ac.yu; dravin@infosky.net; adragan50@hotmail.com

Naučni interes:

  1. Genetska epidemiologija, skrining polimorfizama DNK u genima kandidatima za najčešća oboljenja u populaciji Srbije (vaskularna, neurodegenerativna i renalna), genetska osnova dislipidemija, hipertenzije, dijabetesa, interakcije gen-gen i gen-okolina.

  2. Razvoj i primena tipzacije genoma, u forenzičke svrhe, dijagnostici i terapiji infektivnih oboljenja, kontroli krvnih proizvoda, transplantaciji tkiva i organa, kontroli stočarske proizvodnje, studijama biodiverziteta

Research interest:

  1. Genetic Epidemiology, screening of DNA polzmorphisms in candidate genes for the most common diseases in the Serbian population (vascular, neurodegenerative and renal), genetic involvement in dislipdemia, hzpertension, diabetes, including both gene-gene and gene-environment interactions.
  2. Genome typing application in forensic purpose, both diagnosis and therapy of infectious diseases, control of blood products, tissue and organ transplantation, control of live-stock production, biodiversity research

 

 

 

Spisak radova (MNTR):

  1. Sladić Dj, Cvetković M, Alavantić D, Randjelović M, Simić J, Intestinal absorption of iron in newborn pigs after administration of iron dextran complex per os, Acta Veterinaria, 28(4-6): 209-211, 1978.

  2. Savković N, Pečevski J, Vuksanović Lj, Radivojević D, Alavantić D, Meiotic chromosome translocations male induced by X-irradiation, Strahlentherapie, 159:51-53, 1983.

  3. Pečevski J, Vuksanović Lj, Savković N, Alavantić D, Radivojević D, Effect of sacharin on the induction of chromosomal translocations in male mice and their F1 offspring, Toxicology Letters, 19: 267-271, 1983.

  4. Alavantić D, Searle AG, Effect of post-irradiation interval on translocation frequency in male mice, Mutation Research, 142(1): 65-68, 1985.

  5. Alavantić D, Šunjevarić I, Pečevski J, Cerović G, In vivo genotoxicity of nitrates and nitrites in germ cells of male mice I. Evidence for gonodal exposure and lack of heritable effects, Mutation Research, 204: 689-695, 1988.

  6. Alavantić D, Sunjevarić I, Cerović G, Božin D, Pečevski J, In vivo genotoxicity of nitrates and nitrites in germ cells of male mice II. Uncheduled DNA synthesis and sperm abnormality treatment of spermatids,. Mutation Research, 204, 697-701, 1988.

  7. Glišić S, Šunjevarić I, Alavantić D, Genotyping of apolipoprotein B signal peptide insertion/deletion: a comparison of three methods, Electrophoresis, 16(6): 899-902, 1995.

  8. Glišić S, Savić I, Alavantić D. Apolipoprotein B gene DNA polymor phisms (EcoRI and MspI) and serum lipid levels in the Serbian healthy population: interaction of rare alleles and smoking, and cholesterol levels, Genetic Epidemiology, 12(5): 499-508, 1995.

  9. Glišić S, Alavantić D, A simple PCR with different 3’ ends of the third primer for detection of defined point mutations, Trends in Genetics, 12(10): 391-392, 1996.

  10. Glišić S, Prljić J, Radovanović N, Alavantić D, Study of apoB gene signal peptide insertion/deletion polymorphism in a healthy Serbian population: no association with serum lipid levels, Clinica Chimica Acta, 263: 57-65, 1997.

  11. Alavantić D, Glišić S, Erceg S, Stupar M, Genetic variation at the apoB 3’hypervariable region in Serbian population, Eur J Hum Genet, 5(5): 333-335, 1997.

  12. Alavantić D, Glišić S, Kandić I, The apoB 3’HVR polymorphism in healthy popualation: relationships to serum lipid levels, Genetic Epidemiology, 15: 113-122, 1998

  13. Alavantić D, Glišić S, Radovanović N, Romić M, Medić P, Tomović O, Hepatitis C virus RNA testing by nested PCR in blood preparations in Yugoslavia, Transfusion Science, 19(2): 115-117, 1998.

  14. Alavantić D, Glišić S, Radovanović N, Romić M, A simple PCR with different 3’ ends of the third primer for detection of defined point mutations: HCV genotyping as an example, Clinical Chemistry and Laboratory Medicine, 36(8): 587-588, 1998.

  15. Stanković S, Glišić S, Alavantić D, Apolipoprotein E gene DNA polymorphism in Serbian population, Yugoslav Medical Biochemistry, 18: 9-15, 1999.

  16. Stanković A, Ilić N, Žunić Z, Glišić S, Alavantić D. Association of insertion/deletion polymorphism at the angiotensin I-converting enzyme locus with arterial blood pressure. Yugoslav Medical Biochemistry, 18(4): 141-147, 1999.

  17. Stanković S, Spasojević-Kalimanovska V, Alavantić D. Association of apoE polymorphism with serum lipids in Serbian healthy population, Yugoslav Medical Biochemistry, 19: 115-120, 2000.

  18. Stanković S, Glišić S, Alavantić D. The effect of a gender difference in the apolipoprotein E gene DNA polymorphism on serum lipid levels in a Serbian healthy population, Clin Chem Lab Med 38(6): 539-544, 2000.

  19. Rosser ZH, Zerjal T, Hurles ME, Adojaan M, Alavantić D, …Glišić S,…Tyler-Smith C, Jobling MA. Y-chromosomal diversity within Europe is clinal and influenced primarily by geography rather than language, Am J Hum Genet, 67: 1526-1543, 2000.

  20. Alavantić D, Stanković A. Toward Century of Pharmacogenetics: The role of Genetic Epidemiology with Cardiovascular Diseases as an Example, Yugoslav Medical Biochemistry, 20: 73-80, 2001.

  21. Stanković A, Alavantić D. Rapid detection of the hypertension associated A1166C polymorphism of the angiotensin II type 1 receptor, Genetic Testing, 6: 133-134, 2002.

  22. Stanković A, Živković M, Alavantić D. Angiotensin I-converting enzyme gene polymorphism in a Serbian population: a gender-specific association with hypertension. Scand J Clin Lab Invest. 62: 469-75, 2002.

  23. Stanković A, Živković M, Glišić S, Alavantić D. Angiotensin II type 1 receptor gene polymorphism and essential hypertension in Serbian population. Clin Chim Acta. 327: 181-5, 2003.

Radovi objavljeni u domaćim časopisima:

  1. Vuksanović Lj, Savković N, Pečevski J, Alavantić D, Radivojević D, Cvetković P, Effect of methotrxate on the induction of dominant lethal mutations in male mice, Genetika, 15: 171-175, 1982.

  2. Savković N, Pečevski J, Alavantić D, Vuksanović Lj, Šunjevarić I, Radivojević D, Mutagenicity in mice induced by a commercial mixture of thimet/phorate+lindane, Genetika, 17: 23-28, 1985.

  3. Alavantić D, Pečevski J, Šunjevarić I, Savković N, Vuksanović Lj, Radivojević D, Mutagenicity in mice induced by a commercial mixture "Galition plus", Genetika, 17: 29-34, 1985.

  4. Savković N, Pečevski J, Alavantić D, Šunjevarić I, Radivojević D, The effect of some nutrition additives on dominant lethal mutations induction and sperm abnormalities in mammals, Food and Nutrition, 26: 29-31, 1985.

  5. Alavantić D, Glišić S, Restriction fragment lenght polymorphism - use in the investigation of genetic component of hyperlipidaemia and atherosclerosis, Genetika 22: 147-163, 1990.

  6. Glišić S, Savić I, Knežević V, Alavantić D, Apolipoprotein B gene DNA polymorphisms (EcoRI and MspI) and serum lipid levels in women: the Mladenovac study I, Genetika, 25: 1-9, 1993.

  7. Glišić S, Savić I, Knežević V, Lazović J, Alavantić D, Apolipoprotein B gene DNA polymorphisms (3’hypervariable region) and serum lipid levels in women: the Mladenovac study II, Genetika, 25: 11-19, 1993.

  8. Glišić S, Alavantić D, The Polymorphism Chain Reaction: a method and application. Archive of Oncology 2: 201-207, 1994.

  9. Alavantić D, Stupar M, GlišIć S, DNA fingerprinting: basic principles and application in cancer research, Archive of Oncology, 3: 157-162, 1995.

  10. Glišić S, Alavantić D, Medić P, Romić M, Tomović O, RT-PCR method for investigation of virus hepatitis C genome presence in immunoglobuline preparation, Journal of Military Medicine, 52: 553-556, 1995.

  11. Erceg S, Petrović MP, Trenkovski S, Alavantić D, The identification of breed-specific and individual-specific RAPD markers in sheep, Biotechnology in Animal Husbandry, 15: 11-20, 1999.

  12. Glišić S, Stanković-Đorđević S, Alavantić D, Apolipoprotein E and neurodegenerative diseases: preliminary results of apoE genetic study in the Serbian population, Folia Anatomica, 27: 41-49, 1999.

Poglavlja u domaćim monografijama:

  1. Dimitrijević B, Alavantić D, Restriction maps of mammalian genes and genetic disorders - practical approach, in "Onkogenes and tumor growth factors", (Ed. V. Baltic) SDV, Novi Sad, 65-75, 1988.

  2. Alavantić D, Genotyping of apolipoprotein E: methods and importance, in "Metabolism of lipoproteins and its disorders" (Ed. L.Lepšanović), SLD-DLV, Novi Sad, 181-190, 1997.

  3. Alavantić D, Molecular genetics of hypertension: renin-angiotensin and atrial natriuretic peptide, u "Monographs in Basic and Clinical Medicine: Atrial Natriuretic Peptide" (Ed. Trpinac D, Avramović D), Ecolibri, Beograd, Chpt.12, 99-105, 1997.

  4. Alavantić D, Genome typing: application in pig selection, in "New technologies in pig selection" (Ed. V.Vidović), Aprosim, Novi Sad, 81-88, 1998.

  5. Kostić M, Stanković A, Živković M, Matejić M, Alavantić D, Sajić S, Peco-Antić A, Necić S, Jovanović O, Krušić D. Polimorfizmi gena za Angiotensin I-converting enzyme (ACE) and angiotenzin II type 1 receptor (ATR1) genes in children with insulin dependent diabetes mellitus, in "Diabetic nephropathy" (Ed. Stefanović V.), Sciencia, University of Niš, Niš, 62-66, 2002.

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